Tuesday, March 15, 2016


Dr. Sereda, I was looking over some of the previous year’s quizzes and in the preparation of 5-methyl-2-hexyne from propyne, what would be the nucleophile? Would it be the same as the alkylating agent? Thanks. (The nucleophile is deprotonated alkyne, which attacks the alkylating agent and kicks out the leaving group from it. Overall, it results in the introduction of the alkyl group to the alkyne. - GS).

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