During class when you were talking about Histones and the ability of the amines in them to form spikes, what did you want us to know for that? I understand if there’s a spike in the wound structure of the protein and DNA that it won’t unravel easily but what else is there to know about the importance of Histones and how they relate to the chemistry we are learning now? (Just know that the amino-groups of histones can act as nucleophiles in the nucleophilic acyl substitution with a thioester AcetylCoa. You do not need to know anything from biochemistry for the exam. - GS).