Thursday, November 20, 2014


Could you have a reaction between a carboxylic acid and an amine with a catalyst but without heating? (You need a reagent other than a catalyst, such as a carbodiimid derivative. - GS). Conversely, what about without a catalyst but with heating? Would these yield different answers if there is only one not both? (Either heat or a coupling reagent will produce an amide. - GS).

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