Organic chemistry

This blog is a learning resource for undergraduate students studying organic chemistry. It consists of a database of actual questions and answers about organic chemistry collected by a chemistry professor teaching the subject.

Monday, October 30, 2023

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Can you re-explain why nucleophilicity does not correlate with basicity under protic conditions? (Because the larger particle size decreases...
Wednesday, November 2, 2022

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  Can you clarify the differences between nucleophilicity (Nucleophiles change their ability to donate a pair of electrons in the process o...
Wednesday, October 5, 2022

Markovnikov rule

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 F or which reactions do we use markovnikov’s rule versus anti-markovnikov’s rule? (Regardless of the rule, the preferred reaction proceeds ...
Tuesday, March 16, 2021

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  How can you tell when a reaction goes through the meisenheimer complex or benzyne? (The Meisenheimer complex is formed only in the presenc...
Thursday, October 22, 2020

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  Can you explain in more detail the separation of enantiomers into diastereomers? (A mixture of enantiomers is treated with a chiral reagen...
Tuesday, April 28, 2020

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What should we know regarding fluorescence? I recall discussing the topic in the past but am unable to find my notes regarding. (When a mo...
Monday, April 27, 2020

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E1 reactions are not stereoselective, so would the products be present in a racemic mixture like Sn1? (No. Unlike SN1, E1 does not produce...
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